
Professor In Residence
M_PEDS-HEMATOLOGY
I am an endowed physician and professor in residence at the University of California San Francisco Benioff Children's Hospital in Oakland, California. For nearly 40 years I have been on forefront of research into better treatments and potential cures for hemoglobinopathies. My directorship of the largest and most comprehensive program for individuals with sickle cell disease and their families in the western United States began in 1978. Renamed the UCSF Sickle Cell Center of Excellence and rebuilt stronger, my center continues its mission to improve clinical outcomes and quality of life for individuals living with sickle cell and their families across the lifespan.
Publications
COVID-19 mRNA Vaccination Responses in Individuals With Sickle Cell Disease: ASH RC Sickle Cell Research Network Study.
Blood advances
Disease burden, management strategies, and unmet needs in α-thalassemia due to hemoglobin H disease.
American journal of hematology
Neurocognitive outcome in children with sickle cell disease after myeloimmunoablative conditioning and haploidentical hematopoietic stem cell transplantation: a non-randomized clinical trial.
Frontiers in neurology
Improving healthspan among people with sickle cell disease: Leveraging precision health in an era of treatments with curative intent.
American journal of hematology
Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia.
Hematology/oncology clinics of North America
The Clinical Phenotypes of Alpha Thalassemia.
Hematology/oncology clinics of North America
Assessment of total and unbound cell-free heme in plasma of patients with sickle cell disease.
Experimental biology and medicine (Maywood, N.J.)
COVID-19 Infection and Outcomes in Newborn Screening Cohorts of Sickle Cell Trait and Sickle Cell Disease in Michigan and Georgia.
Journal of pediatric hematology/oncology
The impact of in utero transfusions on perinatal outcomes in patients with alpha thalassemia major: the UCSF registry.
Blood advances
Development of a Thalassemia International Prognostic Scoring System (TIPSS).
Blood cells, molecules & diseases
Safety and efficacy of mitapivat, an oral pyruvate kinase activator, in adults with non-transfusion dependent a-thalassaemia or �-thalassaemia: an open-label, multicentre, phase 2 study.
Lancet (London, England)
The effects of glutamine supplementation on markers of apoptosis and autophagy in sickle cell disease peripheral blood mononuclear cells.
Complementary therapies in medicine
Transitioning Adolescents With Sickle Cell Disease From Pediatric to Adult Care: Results From a New Survey of Health Care Professionals.
Journal of pediatric hematology/oncology
Implications for the metabolic fate of oral glutamine supplementation within plasma and erythrocytes of patients with sickle cell disease: A pharmacokinetics study.
Complementary therapies in medicine
Consensus statement for the perinatal management of patients with alpha thalassemia major.
Blood advances
Risk of mortality from anemia and iron overload in nontransfusion-dependent β-thalassemia.
American journal of hematology
An update on the US adult thalassaemia population: a report from the CDC thalassaemia treatment centres.
British journal of haematology
Anterior Pituitary Volume in Patients with Transfusion Dependent Anemias: Volumetric Approaches and Relation to Pituitary MRI‑R2.
Clinical neuroradiology
Primary HBB gene mutation severity and long-term outcomes in a global cohort of β-thalassaemia.
British journal of haematology
Survival and causes of death in 2033 patients with non-transfusion-dependent ß-thalassemia.
Haematologica
Time to rethink haemoglobin threshold guidelines in sickle cell disease.
British journal of haematology
Pituitary iron and factors predictive of fertility status in transfusion dependent thalassemia.
Haematologica
Stable to improved cardiac and pulmonary function in children with high-risk sickle cell disease following haploidentical stem cell transplantation.
Bone marrow transplantation
Voxelotor in adolescents and adults with sickle cell disease (HOPE): long-term follow-up results of an international, randomised, double-blind, placebo-controlled, phase 3 trial.
The Lancet. Haematology
Voxelotor for the treatment of sickle cell disease.
Expert review of hematology
Iron Deficiency: Implications Before Anemia.
Pediatrics in review
A complication risk score to evaluate clinical severity of thalassaemia syndromes.
British journal of haematology
Effect of Inhaled Cannabis for Pain in Adults With Sickle Cell Disease: A Randomized Clinical Trial.
JAMA network open
Identifying Clinical and Research Priorities in Sickle Cell Lung Disease. An Official American Thoracic Society Workshop Report.
Annals of the American Thoracic Society
Safety and efficacy of deferiprone for pantothenate kinase-associated neurodegeneration: a randomised, double-blind, controlled trial and an open-label extension study.
The Lancet. Neurology
A Phase 3 Randomized Trial of Voxelotor in Sickle Cell Disease.
The New England journal of medicine
Vincristine-induced anemia in hereditary spherocytosis.
Experimental biology and medicine (Maywood, N.J.)
Evaluation of Mandible Fractures in Patients With Sickle Cell Anemia-A Nationwide Study.
Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons
A Phase 3 Trial of l-Glutamine in Sickle Cell Disease.
The New England journal of medicine
Gene Therapy in Patients with Transfusion-Dependent ß-Thalassemia.
The New England journal of medicine
Epidemiologic and clinical characteristics of nontransfusion-dependent thalassemia in the United States.
Pediatric blood & cancer
Fertility and Pregnancy in Women with Transfusion-Dependent Thalassemia.
Hematology/oncology clinics of North America
Sickle cell disease.
Nature reviews. Disease primers
Dietary nonheme iron is equally bioavailable from ferritin or ferrous sulfate in thalassemia intermedia.
Pediatric hematology and oncology
Chronic organ failure in adult sickle cell disease.
Hematology. American Society of Hematology. Education Program
Variability of homozygous sickle cell disease: The role of alpha and beta globin chain variation and other factors.
Blood cells, molecules & diseases
Encephaloduroarteriosynangiosis (EDAS) in young patients with cerebrovascular complications of sickle cell disease: Single-institution experience.
Pediatric hematology and oncology
Lifespan care in SCD: Whom to transition, the patients or the health care system?
American journal of hematology
Simvastatin reduces vaso-occlusive pain in sickle cell anaemia: a pilot efficacy trial.
British journal of haematology
Long-term safety and efficacy of deferasirox in young pediatric patients with transfusional hemosiderosis: Results from a 5-year observational study (ENTRUST).
Pediatric blood & cancer
Emergency department utilization by Californians with sickle cell disease, 2005-2014.
Pediatric blood & cancer
Favorable outcomes after in utero transfusion in fetuses with alpha thalassemia major: a case series and review of the literature.
Prenatal diagnosis
Non-transfusion-dependent thalassemia and thalassemia intermedia: epidemiology, complications, and management.
Current medical research and opinion
Fertility in transfusion-dependent thalassemia men: effects of iron burden on the reproductive axis.
American journal of hematology
Dysregulated arginine metabolism and cardiopulmonary dysfunction in patients with thalassaemia.
British journal of haematology
Is the medical home for adult patients with sickle cell disease a reality or an illusion?
Hemoglobin
In utero hematopoietic cell transplantation for hemoglobinopathies.
Frontiers in pharmacology
Mechanisms of plasma non-transferrin bound iron generation: insights from comparing transfused diamond blackfan anaemia with sickle cell and thalassaemia patients.
British journal of haematology
Population based surveillance in sickle cell disease: methods, findings and implications from the California registry and surveillance system in hemoglobinopathies project (RuSH).
Pediatric blood & cancer
Emerging Therapies Targeting the Pathophysiology of Sickle Cell Disease
Hematology/oncology clinics of North America
Relationship among chelator adherence, change in chelators, and quality of life in thalassemia.
Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation
Elevated tricuspid regurgitant jet velocity in subgroups of thalassemia patients: insight into pathophysiology and the effect of splenectomy.
Annals of hematology
Neuroimaging abnormalities in adults with sickle cell anemia: associations with cognition.
Neurology
Emerging therapy in hemoglobinopathies: lessons from the past and optimism for the future.
Hematology/oncology clinics of North America
Validation and reliability of a disease-specific quality of life measure (the TranQol) in adults and children with thalassaemia major.
British journal of haematology
Pain over time and its effects on life in thalassemia.
American journal of hematology
Renal medullary carcinoma in an adolescent with sickle cell anemia.
Pediatric blood & cancer
Efficacy and safety of deferasirox compared with deferoxamine in sickle cell disease: two-year results including pharmacokinetics and concomitant hydroxyurea.
American journal of hematology
Zinc supplementation improves bone density in patients with thalassemia: a double-blind, randomized, placebo-controlled trial.
The American journal of clinical nutrition
Treatment of classic pantothenate kinase-associated neurodegeneration with deferiprone and intrathecal baclofen.
American journal of physical medicine & rehabilitation
Pregnancy outcomes in women with thalassemia in North America and the United Kingdom.
American journal of hematology
Non-transfusion-dependent thalassemias.
Haematologica
Treatment of heart failure in adults with thalassemia major: response in patients randomised to deferoxamine with or without deferiprone.
Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
Clinical manifestations of a-thalassemia.
Cold Spring Harbor perspectives in medicine
The palatability and tolerability of deferasirox taken with different beverages or foods.
Pediatric blood & cancer
Sildenafil therapy in thalassemia patients with Doppler-defined risk of pulmonary hypertension.
Haematologica
Human T cell lymphotropic virus type 1 infection among U.S. thalassemia patients.
AIDS research and human retroviruses
Pain in thalassaemia: the effects of age on pain frequency and severity.
British journal of haematology
Increased leucocyte apoptosis in transfused ß-thalassaemia patients.
British journal of haematology
Combined chelation therapy with deferasirox and deferoxamine in thalassemia.
Blood cells, molecules & diseases
A phase 1/2 trial of HQK-1001, an oral fetal globin inducer, in sickle cell disease.
American journal of hematology
The effect of whole body vibration therapy on bone density in patients with thalassemia: a pilot study.
American journal of hematology
Inadequate dietary intake in patients with thalassemia.
Journal of the Academy of Nutrition and Dietetics
A potent oral P-selectin blocking agent improves microcirculatory blood flow and a marker of endothelial cell injury in patients with sickle cell disease.
American journal of hematology
Advances in the treatment of alpha-thalassemia.
Blood reviews
British Journal of Haematology
Safety of deferasirox in sickle cell disease patients with co-existing liver impairment – response to Sinakos et al
Emerging 'A' therapies in hemoglobinopathies: agonists, antagonists, antioxidants, and arginine.
Hematology. American Society of Hematology. Education Program
The prevention and management of alloimmunization in sickle cell disease: the benefit of extended phenotypic matching of red blood cells.
Immunohematology
Hb E/beta-thalassaemia: a common & clinically diverse disorder.
The Indian journal of medical research
Long-term safety and efficacy of deferasirox (Exjade) for up to 5 years in transfusional iron-overloaded patients with sickle cell disease.
British journal of haematology
Iron chelation adherence to deferoxamine and deferasirox in thalassemia.
American journal of hematology
Darbepoetin alfa for the treatment of anaemia in alpha- or beta- thalassaemia intermedia syndromes.
British journal of haematology
A pilot study of the short-term use of simvastatin in sickle cell disease: effects on markers of vascular dysfunction.
British journal of haematology
The mediating effects of family functioning on psychosocial outcomes in healthy siblings of children with sickle cell disease.
Pediatric blood & cancer
Heterogeneity of hemoglobin H disease in childhood.
The New England journal of medicine
Red cell alloimmunization in a diverse population of transfused patients with thalassaemia.
British journal of haematology
The effects of hydroxycarbamide and magnesium on haemoglobin SC disease: results of the multi-centre CHAMPS trial
British journal of haematology
Novel influenza A (H1N1) viral infection in pediatric patients with sickle-cell disease.
Pediatric blood & cancer
HbE/ß-thalassemia: basis of marked clinical diversity.
Hematology/oncology clinics of North America
Chart Card: feasibility of a tool for improving emergency department care in sickle cell disease.
Journal of the National Medical Association
Education and employment status of children and adults with thalassemia in North America.
Pediatric blood & cancer
Complexity of alpha thalassemia: growing health problem with new approaches to screening, diagnosis, and therapy.
Annals of the New York Academy of Sciences
Fertility potential in thalassemia major women: current findings and future diagnostic tools.
Annals of the New York Academy of Sciences
Preface to Cooley's Anemia: Ninth Symposium.
Annals of the New York Academy of Sciences
Pulmonary hypertension in thalassemia.
Annals of the New York Academy of Sciences
Approaches to transfusion therapy and iron overload in patients with sickle cell disease: results of an international survey.
Pediatric hematology and oncology
Transfusion and chelation practices in sickle cell disease: a regional perspective.
Pediatric hematology and oncology
Relationship between chronic transfusion therapy and body composition in subjects with thalassemia.
The Journal of pediatrics
Elevated exhaled carbon monoxide concentration in hemoglobinopathies and its relation to red blood cell transfusion therapy.
Pediatric hematology and oncology
Pulmonary hypertension in hemolytic anemias.
F1000 medicine reports
Hemoglobin Hakkari: an autosomal dominant form of beta thalassemia with inclusion bodies arising from de novo mutation in exon 2 of beta globin gene.
Pediatric blood & cancer
Assessment of cardiac iron by MRI susceptometry and R2* in patients with thalassemia.
Magnetic resonance imaging
Low dose, oral epsilon aminocaproic acid for renal papillary necrosis and massive hemorrhage in hemoglobin SC disease.
Pediatric blood & cancer
Application of an expanded multiplex genotyping assay for the simultaneous detection of Hemoglobin Constant Spring and common deletional alpha-thalassemia mutations.
International journal of laboratory hematology
Iron metabolism and iron chelation in sickle cell disease.
Acta haematologica
Hemoglobin H-constant spring in North America: an alpha thalassemia with frequent complications.
American journal of hematology
Severe sickle cell disease--pathophysiology and therapy.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Efficacy and safety of deferasirox doses of >30 mg/kg per d in patients with transfusion-dependent anaemia and iron overload.
British journal of haematology
Differences in the prevalence of growth, endocrine and vitamin D abnormalities among the various thalassaemia syndromes in North America.
British journal of haematology
HLA type and risk of alloimmunization in sickle cell disease.
American journal of hematology
Newborn screening for hemoglobinopathies in California.
Pediatric blood & cancer
Bone disease in thalassemia: a frequent and still unresolved problem.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
Alpha thalassemia major--new mutations, intrauterine management, and outcomes.
Hematology. American Society of Hematology. Education Program
Pulmonary complications of sickle cell disease.
The New England journal of medicine
Hemoglobinopathies.
Current molecular medicine
Hydroxycarbamide-induced changes in E/beta thalassemia red blood cells.
American journal of hematology
Psychosocial and behavioral outcomes in children with sickle cell disease and their healthy siblings.
Journal of behavioral medicine
Detection and assessment of stroke in patients with sickle cell disease: neuropsychological functioning and magnetic resonance imaging.
Pediatric hematology and oncology
Oral iron chelators and the treatment of iron overload in pediatric patients with chronic anemia.
Pediatrics
An expanded Transactional Stress and Coping Model for siblings of children with sickle cell disease: family functioning and sibling coping, self-efficacy and perceived social support.
Child: care, health and development
Clinical application of deferasirox: practical patient management.
American journal of hematology
Advances in clinical research in sickle cell disease.
British journal of haematology
Transfusional iron burden and liver toxicity after bone marrow transplantation for acute myelogenous leukemia and hemoglobinopathies.
Pediatric blood & cancer
Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study.
European journal of haematology
Clinical differences between children and adults with pulmonary hypertension and sickle cell disease.
British journal of haematology
Serum ferritin underestimates liver iron concentration in transfusion independent thalassemia patients as compared to regularly transfused thalassemia and sickle cell patients.
Pediatric blood & cancer
Phase Ib clinical trial of starch-conjugated deferoxamine (40SD02): a novel long-acting iron chelator.
British journal of haematology
Iron homeostasis during transfusional iron overload in beta-thalassemia and sickle cell disease: changes in iron regulatory protein, hepcidin, and ferritin expression.
Pediatric hematology and oncology
Prospective evaluation of patient-reported outcomes during treatment with deferasirox or deferoxamine for iron overload in patients with beta-thalassemia.
Clinical therapeutics
Morbidity and mortality in chronically transfused subjects with thalassemia and sickle cell disease: A report from the multi-center study of iron overload.
American journal of hematology
A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease.
British journal of haematology
Caregiving time in sickle cell disease: psychological effects in maternal caregivers.
Pediatric blood & cancer
Hemoglobin e syndromes.
Hematology. American Society of Hematology. Education Program
Bone mineral density in children with sickle cell anemia.
Pediatric blood & cancer
Physical therapy alone compared with core decompression and physical therapy for femoral head osteonecrosis in sickle cell disease. Results of a multicenter study at a mean of three years after treatment.
The Journal of bone and joint surgery. American volume
Increased prevalence of iron-overload associated endocrinopathy in thalassaemia versus sickle-cell disease.
British journal of haematology
Oxidative stress and inflammation in iron-overloaded patients with beta-thalassaemia or sickle cell disease.
British journal of haematology
Prevalence of HFE mutations in California newborns.
Pediatric hematology and oncology
Pulmonary hypertension in thalassemia: association with platelet activation and hypercoagulable state.
American journal of hematology
Pulmonary hypertension in thalassaemia major patients with normal left ventricular systolic function.
British journal of haematology
Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait.
Journal of the National Medical Association
Fetal haemoglobin augmentation in E/beta(0) thalassaemia: clinical and haematological outcome.
British journal of haematology
Bone and joint disease in sickle cell disease.
Hematology/oncology clinics of North America
Comparison of organ dysfunction in transfused patients with SCD or beta thalassemia.
American journal of hematology
Clinical evaluation of avascular necrosis in patients with sickle cell disease: Children's Hospital Oakland Hip Evaluation Scale--a modification of the Harris Hip Score.
Archives of physical medicine and rehabilitation
Barriers to adherence of deferoxamine usage in sickle cell disease.
Pediatric blood & cancer
A simple model to assess and improve adherence to iron chelation therapy with deferoxamine in patients with thalassemia.
Annals of the New York Academy of Sciences
Changing patterns of thalassemia worldwide.
Annals of the New York Academy of Sciences
Hemoglobin E-beta-thalassemia: Progress report from the International Study Group.
Annals of the New York Academy of Sciences
Hemolysis-associated pulmonary hypertension in thalassemia.
Annals of the New York Academy of Sciences
Measuring chromosome breaks in patients with thalassemia.
Annals of the New York Academy of Sciences
Outcomes of preimplantation genetic diagnosis therapy in treatment of beta-thalassemia: A retrospective analysis.
Annals of the New York Academy of Sciences
Quality of life in patients with thalassemia intermedia compared to thalassemia major.
Annals of the New York Academy of Sciences
Single and combination drug therapy for fetal hemoglobin augmentation in hemoglobin E-beta 0-thalassemia: Considerations for treatment.
Annals of the New York Academy of Sciences
Treatment of hepatitis C virus infection in thalassemia.
Annals of the New York Academy of Sciences
Utility of Holter electrocardiogram in iron-overloaded hemoglobinopathies.
Annals of the New York Academy of Sciences
Variability in hepatic iron concentration in percutaneous needle biopsy specimens from patients with transfusional hemosiderosis.
American journal of clinical pathology
Hematologic problems in immigrants from Southeast Asia.
Hematology/oncology clinics of North America
The new SQUID biosusceptometer at Oakland: first year of experience.
Neurology & clinical neurophysiology : NCN
Can peak systolic velocities be used for prediction of stroke in sickle cell anemia?
Pediatric radiology
Thalassemia in Sri Lanka: a progress report.
Human molecular genetics
The role of fetal hemoglobin-enhancing agents in thalassemia.
Seminars in Hematology
Pulmonary hypertension in sickle cell disease.
The New England journal of medicine
Thalassemia.
Hematology. American Society of Hematology. Education Program
Managing sickle cell disease.
BMJ (Clinical research ed.)
Invasive pneumococcal infections in children with sickle cell disease in the era of penicillin prophylaxis, antibiotic resistance, and 23-valent pneumococcal polysaccharide vaccination.
The Journal of pediatrics
Hydroxyurea and arginine therapy: impact on nitric oxide production in sickle cell disease.
Journal of pediatric hematology/oncology
Liver ferritin subunit ratios in neonatal hemochromatosis.
Pediatric hematology and oncology
Arginine therapy: a new treatment for pulmonary hypertension in sickle cell disease?
American journal of respiratory and critical care medicine
Chlamydia pneumoniae and acute chest syndrome in patients with sickle cell disease.
Journal of pediatric hematology/oncology
Pancytopenia induced by hypothermia.
Journal of pediatric hematology/oncology
Diseases of iron metabolism.
Pediatric clinics of North America
New therapies in sickle cell disease.
Lancet (London, England)
Bioelectrical impedance analysis of the body composition of children and adolescents with sickle cell disease.
The Journal of pediatrics
Longitudinal changes in ferritin during chronic transfusion: a report from the Stroke Prevention Trial in Sickle Cell Anemia (STOP).
Journal of pediatric hematology/oncology
Assessment of sickle cell pain in children and young adults using the adolescent pediatric pain tool.
Journal of pain and symptom management
Central venous catheter complications in sickle cell disease.
American journal of hematology
Effect of hydroxyurea on growth in children with sickle cell anemia: results of the HUG-KIDS Study.
The Journal of pediatrics
Using quality improvement strategies to enhance pediatric pain assessment.
International journal for quality in health care : journal of the International Society for Quality in Health Care
Novel therapeutic approaches in sickle cell disease.
Hematology. American Society of Hematology. Education Program
Silent infarcts in children with sickle cell anemia and abnormal cerebral artery velocity.
Archives of neurology
A novel multilocus genotyping assay to identify genetic predictors of stroke in sickle cell anaemia.
British journal of haematology
Neuropsychologic performance in school-aged children with sickle cell disease: a report from the Cooperative Study of Sickle Cell Disease.
The Journal of pediatrics
Silent infarction as a risk factor for overt stroke in children with sickle cell anemia: a report from the Cooperative Study of Sickle Cell Disease.
The Journal of pediatrics
Transfusion therapy: a coming-of-age treatment for patients with sickle cell disease.
Journal of pediatric hematology/oncology
Nesidioblastosis in sickle cell disease.
Pediatric pathology & molecular medicine
Consensus document for transfusion-related iron overload.
Seminars in Hematology
Current issues with blood transfusions in sickle cell disease.
Seminars in Hematology
Stable mixed hematopoietic chimerism after bone marrow transplantation for sickle cell anemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
Stem cell transplantation for sickle cell disease: can we reduce the toxicity?
Pediatric pathology & molecular medicine
Universal newborn screening for Hb H disease in California.
Genetic testing
Arginine therapy: a novel strategy to induce nitric oxide production in sickle cell disease.
British journal of haematology
Changing outcome of homozygous alpha-thalassemia: cautious optimism.
Journal of pediatric hematology/oncology
Outreach strategies for Southeast Asian communities: experience, practice, and suggestions for approaching Southeast Asian immigrant and refugee communities to provide thalassemia education and trait testing.
Journal of pediatric hematology/oncology
Patterns of arginine and nitric oxide in patients with sickle cell disease with vaso-occlusive crisis and acute chest syndrome.
Journal of pediatric hematology/oncology
Multicenter comparison of magnetic resonance imaging and transcranial Doppler ultrasonography in the evaluation of the central nervous system in children with sickle cell disease.
Journal of pediatric hematology/oncology
Use of hydroxyurea in children ages 2 to 5 years with sickle cell disease.
Journal of pediatric hematology/oncology
Causes and outcomes of the acute chest syndrome in sickle cell disease. National Acute Chest Syndrome Study Group.
The New England journal of medicine
Sickle-cell disease not identified by newborn screening because of prior transfusion.
The Journal of pediatrics
Major changes in sickle cell disease.
Advances in pediatrics
Hydroxyurea and sodium phenylbutyrate therapy in thalassemia intermedia.
American journal of hematology
The perioperative complication rate of orthopedic surgery in sickle cell disease: report of the National Sickle Cell Surgery Study Group.
American journal of hematology
Transfusion practice for patients with sickle cell disease.
Current opinion in hematology
Bone disease in beta-thalassaemia.
Lancet (London, England)
Effects of red blood cell transfusion on resting energy expenditure in adolescents with sickle cell anemia.
Journal of pediatric gastroenterology and nutrition
Clinician assessment for acute chest syndrome in febrile patients with sickle cell disease: is it accurate enough?
Annals of Emergency Medicine
Role of positron emission tomography in determining the extent of CNS ischemia in patients with sickle cell disease.
American journal of hematology
Tonsillectomy, adenoidectomy, and myringotomy in sickle cell disease: perioperative morbidity. Preoperative Transfusion in Sickle Cell Disease Study Group.
Journal of pediatric hematology/oncology
Deferoxamine treatment during pregnancy: is it harmful?
American journal of hematology
Erythrocytapheresis for chronically transfused children with sickle cell disease: an effective method for maintaining a low hemoglobin S level and reducing iron overload.
Journal of clinical apheresis
Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography.
The New England journal of medicine
Approaches to working with adult thalassemia patients in pediatric settings.
Annals of the New York Academy of Sciences
Bone marrow transplant in thalassemia. A role for radiation?
Annals of the New York Academy of Sciences
Outreach strategies for Asian Pacific Island (API) communities.
Annals of the New York Academy of Sciences
Preliminary report: hydroxyurea produces significant clinical response in thalassemia intermedia.
Annals of the New York Academy of Sciences
The hemoglobin E syndromes.
Annals of the New York Academy of Sciences
The morbidity of bone disease in thalassemia.
Annals of the New York Academy of Sciences
The social impact of migration on disease. Cooley's anemia, thalassemia, and new Asian immigrants.
Annals of the New York Academy of Sciences
Correction of the anemia of epidermolysis bullosa with intravenous iron and erythropoietin.
The Journal of pediatrics
Acute chest syndrome and sickle cell disease.
Current opinion in hematology
Stroke prevention trial in sickle cell anemia.
Controlled clinical trials
Surgery in patients with hemoglobin SC disease. Preoperative Transfusion in Sickle Cell Disease Study Group.
American journal of hematology
The natural history of sickle cell disease.
Current opinion in pediatrics
Hydroxyurea in children with sickle cell disease: impact on splenic function and compliance with therapy.
Journal of pediatric hematology/oncology
New considerations in the treatment of sickle cell disease.
Annual review of medicine
Hydroxyurea in children: present and future.
Seminars in Hematology
Influence of penicillin prophylaxis on antimicrobial resistance in nasopharyngeal S. pneumoniae among children with sickle cell anemia. The Ancillary Nasopharyngeal Culture Study of Prophylactic Penicillin Study II.
Journal of pediatric hematology/oncology
Umbilical cord blood stem cells: application for the treatment of patients with hemoglobinopathies.
The Journal of pediatrics
Natural history of blood pressure in sickle cell disease: risks for stroke and death associated with relative hypertension in sickle cell anemia.
The American journal of medicine
New therapies and approaches to transfusion in sickle cell disease in children.
Current opinion in pediatrics
Pulmonary complications.
Hematology/oncology clinics of North America
Serotype-specific immunoglobulin G antibody responses to pneumococcal polysaccharide vaccine in children with sickle cell anemia: effects of continued penicillin prophylaxis.
The Journal of pediatrics
Core decompression in avascular necrosis of the hip in sickle-cell disease.
American journal of hematology
Barriers to bone marrow transplantation for sickle cell anemia.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation
The spectrum of brain MR abnormalities in sickle-cell disease: a report from the Cooperative Study of Sickle Cell Disease.
AJNR. American journal of neuroradiology
Newborn screening for sickle cell disease: 4 years of experience from California's newborn screening program.
Journal of pediatric hematology/oncology
Ototoxicity in hemoglobinopathy patients chelated with desferrioxamine.
Journal of pediatric hematology/oncology
Discontinuing penicillin prophylaxis in children with sickle cell anemia. Prophylactic Penicillin Study II.
The Journal of pediatrics
A comparison of conservative and aggressive transfusion regimens in the perioperative management of sickle cell disease. The Preoperative Transfusion in Sickle Cell Disease Study Group.
The New England journal of medicine
Risk of recurrent stroke in patients with sickle cell disease treated with erythrocyte transfusions.
The Journal of pediatrics
Liver transplantation in a child with sickle cell anemia.
Transplantation
Effects of a long-term transfusion regimen on sickle cell-related illnesses.
The Journal of pediatrics
Pulmonary fat embolism: a distinct cause of severe acute chest syndrome in sickle cell anemia.
Blood
New advances in the pathophysiology and management of sickle cell disease.
Current opinion in hematology
Availability of related donors for bone marrow transplantation in sickle cell anemia.
The American journal of pediatric hematology/oncology
Butyrate derivatives. New agents for stimulating fetal globin production in the beta-globin disorders.
The American journal of pediatric hematology/oncology
Universal screening for hemoglobinopathies using high-performance liquid chromatography: clinical results of 2.2 million screens.
European journal of human genetics : EJHG
Detection of Hb E/beta-thalassemia versus homozygous EE using high-performance liquid chromatography results from newborns.
Biochemical medicine and metabolic biology
A short-term trial of butyrate to stimulate fetal-globin-gene expression in the beta-globin disorders.
The New England journal of medicine
Differentiation of homozygous hemoglobin E from compound heterozygous hemoglobin E-beta O-thalassemia by hemoglobin E mutation analysis.
The Journal of pediatrics
Sickle cell disease in a patient with sickle cell trait and compound heterozygosity for hemoglobin S and hemoglobin Quebec-Chori.
The New England journal of medicine
Pain in sickle cell disease. Rates and risk factors.
The New England journal of medicine
Comprehensive care in sickle cell disease: its impact on morbidity and mortality.
Seminars in Hematology
Alloimmunization in sickle cell anemia and transfusion of racially unmatched blood.
The New England journal of medicine
Vitamin C deficiency in patients with sickle cell anemia.
The American journal of pediatric hematology/oncology
Elevated fasting breath hydrogen and abnormal hydrogen breath tests in children with sickle cell disease: a preliminary report.
The American journal of clinical nutrition
Butyrate analogues modulate globin gene expression in human and ovine erythroid cells.
Progress in clinical and biological research
Hematopoietic hormones: from cloning to clinic.
The American journal of pediatric hematology/oncology
Contraceptive use in the chronically ill adolescent female.
Journal of adolescent health care : official publication of the Society for Adolescent Medicine
Suggested guidelines for the treatment of children with sickle cell anemia.
Hematology/oncology clinics of North America
Prophylaxis with oral penicillin in children with sickle cell anemia. A randomized trial.
The New England journal of medicine
Growth retardation in sickle-cell disease treated by nutritional support.
Lancet (London, England)
Long-term follow-up and booster immunization with polyvalent pneumococcal polysaccharide in patients with sickle cell anemia.
The Journal of pediatrics
Inadequate erythroid response to hypoxia in cystic fibrosis.
The Journal of pediatrics
Evidence for a heterogeneous response to erythropoietin in the CFUE pool of human bone marrow.
Experimental hematology
Iron deficiency in health and disease.
Advances in pediatrics
Concurrent sickle-cell anemia and alpha-thalassemia: effect on severity of anemia.
The New England journal of medicine
Multidisciplinary approach to pain management in sickle cell disease.
The American journal of pediatric hematology/oncology
Peroxidation, vitamin E, and sickle-cell anemia.
Annals of the New York Academy of Sciences
Current treatment of sickle cell disease.
Current problems in pediatrics
Sickle cell anemia and related hemoglobinopathies.
Pediatric clinics of North America
Unstable hemoglobins, hemoglobins with altered oxygen affinity, and m-hemoglobins.
Pediatric clinics of North America
Fetal Hb production during acute erythroid expansion. I. Observations in patients with transient erythroblastopenia and post-phlebotomy.
British journal of haematology
Anemia in the newborn period.
Pediatric annals
Anemia associated with rheumatoid arthritis.
The Journal of pediatrics
Immune response after splenectomy.
Lancet (London, England)
Preparation and properties of a cell-free system from rat skin that catalyzes sterol biosynthesis.
Journal of lipid research
Guidelines for the Management of Non Tranfusion Dependent Thalassemia (NTDT). Thalassemia International Federation, 2013
Guidelines for the Management of Non Tranfusion Dependent Thalassemia (NTDT). Thalassemia International Federation, 2013.